VWD1 - Von Willebrand's Disease Type I/Austrian Pinscher

Race liée: 

Mild bleeding disorder

Description: 
Insufficient synthesis of von Willebrand factor, a protein involved in blood coagulation
Symptomes: 
Important bleedings or haemorrhagic episodes, potentially lethal only after a surgical act or trauma. Spontaneous bleedings of mucous membranes observed in very rare cases
Age d'aparition: 
From birth
Gène impliqué: 
VWF
Mutation testée: 
c.7142C>T
Transmission: 
Autosomal Recessive
Remarques: 
"Attenuate symptoms can exceptionally be observed in heterozygous dogs"