HFH-B - Hereditary Footpad Hyperkeratosis / French Mastiff

Corny Feet

Description: 
Thickening and hardening of footpads resulting from abnormal proliferation of epidermal cells.
Symptomes: 
Horny protrusions on all footpads, fissures and cracks possibly causing great pain and therefore reduced mobility of the dog.
Age d'aparition: 
Between 4 and 9 months old
Fréquence: 
11% carriers in French population
Transmission: 
Autosomal Recessive
Remarques: 
The research was led by the team of Dr. Catherine André (CNRS of Rennes, France) in collaboration with Antagene.