ERYN - Neonatal Isoerythrolysis/Générique

Poisoning of the kitten by the maternal milk

Description: 
There are three feline blood groups: A, B and AB (currently appears to be rare). Blood group A cats have some naturally occurring anti-B antibodies in their blood, whereas blood group B cats all have naturally occurring anti-A antibodies that are present in high levels. These natural antibodies can cause neonatal isoerythrolysis in kittens. The problem mainly arises if a queen with blood group B produces kittens that are blood group A. During their first day of life, kittens absorb antibodies from the mother's colostrum (first milk) which destroy their red blood cells.
Symptomes: 
Brownish-red urine, jaundice, tail tip necrosis, anaemia potentially fatal for the kitten
Age d'aparition: 
From birth
Fréquence: 
According to breeds, the frequency of group B is more or less considerable
Gène impliqué: 
CMAH
Mutation testée: 
_
Transmission: 
Autosomal Recessive
Brevet: 
_
Remarques: 
Blood group B cats are homozygous for b allele. This b allele is recessive to the allele for groups A and AB. The cat blood group DNA test can genetically characterize the blood group of breeding cats, identify cats that carrier b allele for mate selection to avoid production of neonatal isoerythrolysis kittens.