CMO - Craniomandibular Osteopathy/Générique

Bone proliferation

Description: 
Non-cancerous proliferating disease altering form and function of the bones of the skull and jaw bone
Symptomes: 
During the bony proliferation phase, difficulties in chewing, swelling and thickening of the jaw, pain, recurrent fever
Age d'aparition: 
Between 4 and 7 months old
Fréquence: 
Not available
Gène impliqué: 
SLC37A2
Mutation testée: 
c.1332C>T
Transmission: 
Autosomal Dominant with incomplete penetrance
Brevet: 
-
Remarques: 
Because of incomplete penetrance and varying expressivity, many of the dogs carrying the CMO mutation will live without showing clinical signs