ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
Neuromuscular dysfunction
Description: Neurometabolic disorder characterised by elevated level of L-2-hydroxyglutaric acid in urine, plasma and cerebrospinal fluid
Symptoms : Seizures, "wobbly" gait, tremors, muscle stiffness, dementia
Age of onset : From the age of 6 months
Frequency : 8%
Gene involved : L2HGDH
Tested mutation : c.1297T>C and c.1299C>T
Transmission : Autosomal Recessive
Patent : _
Notes : _
Progressive loss of vision
Description: Bilateral and progressive lens opacity
Symptoms : Progressive loss of vision culminating in blindness
Age of onset : from a few weeks to months old
Frequency : 8% carriers in French pop
Gene involved : HSF4
Tested mutation : g.85286582_insC
Transmission : Autosomal Recessive
Patent : _
Notes : _
Lighter black or brown coat colour
Description: DNA test can identifying dogs carrying the genotype "Dilute" (D Locus)
Symptoms : Dilution or lightening effect of the black or brown colours
Age of onset : From birth
Frequency : _
Gene involved : MLPH
Tested mutation : c.-22G>A
Transmission : Autosomal Recessive
Patent : _
Notes : _
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten
ANTAGENE produces an unique genetic fingerprint of a dog or a cat
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Tail chasing
Speciality Neurology
Description : Disease classified as an obsessive compulsive disorder
Symptoms : Affected dogs spin rapidly in tight circles, more or less frequently, with or without apparent interest in the tail.
Age of onset : -
Examination : Neurological check-up
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. Escriou (VetAgro Sup, France), veterinary neurologist and team of Dr H. Lohi (University of Helsinki, Finland)
Contact : spinning@vetagro-sup.fr mageane@antagene.com
Comment : -
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Tail chasing
Speciality Neurology
Description : Disease classified as an obsessive compulsive disorder
Symptoms : Affected dogs spin rapidly in tight circles, more or less frequently, with or without apparent interest in the tail.
Age of onset : -
Examination : Neurological check-up
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. Escriou (VetAgro Sup, France), veterinary neurologist and team of Dr H. Lohi (University of Helsinki, Finland)
Contact : spinning@vetagro-sup.fr mageane@antagene.com
Comment : -