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Staffordshire Bull Terrier
Staffordshire Bull Terrier
Antagene Séléction
DNA - based testing for hereditary diseases
ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
L2HGA - L-2-Hydroxyglutaric Aciduria
Neuromuscular dysfunction
Staffordshire Bull Terrier
L2HGA - L-2-Hydroxyglutaric Aciduria
Description: Neurometabolic disorder characterised by elevated level of L-2-hydroxyglutaric acid in urine, plasma and cerebrospinal fluid
Symptoms : Seizures, "wobbly" gait, tremors, muscle stiffness, dementia
Age of onset : From the age of 6 months
Frequency : 8%
Gene involved : L2HGDH
Tested mutation : c.1297T>C and c.1299C>T
Transmission : Autosomal Recessive
Patent : _
Notes : _
HC - Hereditary Cataract
Progressive loss of vision
Staffordshire Bull Terrier
HC - Hereditary Cataract
Description: Bilateral and progressive lens opacity
Symptoms : Progressive loss of vision culminating in blindness
Age of onset : from a few weeks to months old
Frequency : 8% carriers in French pop
Gene involved : HSF4
Tested mutation : g.85286582_insC
Transmission : Autosomal Recessive
Patent : _
Notes : _
DIL - Dilution
Lighter coat colour
Staffordshire Bull Terrier
DIL - Dilution
Description: DNA test can identifying dogs carrying the genotype "Dilute" (D Locus)
Symptoms : Dilution or lightening effect of the solid colours
Age of onset : From birth
Frequency : _
Gene involved : MLPH
Tested mutation : c.-22G>A
Transmission : Autosomal Recessive
Patent : _
Notes : _
Antagene Parenté
DNA - Certified parentage
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten
Antagene Identité
Genetic Identification
ANTAGENE produces an unique genetic fingerprint of a dog or a cat
Programme de recherche
Research program
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Spinning
Tail chasing
Staffordshire Bull Terrier
Spinning
Speciality Neurology
Description : Disease classified as an obsessive compulsive disorder
Symptoms : Affected dogs spin rapidly in tight circles, more or less frequently, with or without apparent interest in the tail.
Age of onset : -
Examination : Neurological check-up
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. Escriou (VetAgro Sup, France), veterinary neurologist and team of Dr H. Lohi (University of Helsinki, Finland)
Contact : spinning@vetagro-sup.fr mageane@antagene.com
Comment : -
Programme de recherche
Research program
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Spinning
Tail chasing
Staffordshire Bull Terrier
Spinning
Speciality Neurology
Description : Disease classified as an obsessive compulsive disorder
Symptoms : Affected dogs spin rapidly in tight circles, more or less frequently, with or without apparent interest in the tail.
Age of onset : -
Examination : Neurological check-up
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. Escriou (VetAgro Sup, France), veterinary neurologist and team of Dr H. Lohi (University of Helsinki, Finland)
Contact : spinning@vetagro-sup.fr mageane@antagene.com
Comment : -