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Scottish Terrier
Scottish Terrier
Antagene Séléction
DNA - based testing for hereditary diseases
ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
CMO - Craniomandibular Osteopathy
Bone proliferation
Scottish Terrier
CMO - Craniomandibular Osteopathy
Description: Non-cancerous proliferating disease altering form and function of the bones of the skull and jaw bone
Symptoms : During the bony proliferation phase, difficulties in chewing, swelling and thickening of the jaw, pain, recurrent fever
Age of onset : Between 4 and 7 months old
Frequency : Not available
Gene involved : SLC37A2
Tested mutation : c.1332C>T
Transmission : Autosomal Dominant with incomplete penetrance
Patent : -
Notes : Because of incomplete penetrance and varying expressivity, many of the dogs carrying the CMO mutation will live without showing clinical signs
VWD3-A - von Willebrand's Disease Type III
Severe bleeding disorder
Scottish Terrier
VWD3-A - von Willebrand's Disease Type III
Description: Lack of von Willebrand factor synthesis, a protein involved in blood coagulation
Symptoms : Important or severe bleeding disorders, difficult to contain, leading to death
Age of onset : From birth
Frequency : 15%
Gene involved : VWF
Tested mutation : c.264delC
Transmission : Autosomal Recessive
Patent : _
Notes : _
INT - I Locus
Intensity of the red coat pigment
Scottish Terrier
INT - I Locus
Description: Lightening of the red pigment (phaeomelanin)
Symptoms : Silver, light fawn, cream, white coat... depending on breeds
Age of onset : From birth
Frequency : -
Gene involved : MFSD12
Tested mutation : c.151C>T
Transmission : Autosomal Recessive
Patent : -
Notes : -
Antagene Parenté
DNA - Certified parentage
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten
Antagene Identité
Genetic Identification
ANTAGENE produces an unique genetic fingerprint of a dog or a cat
Programme de recherche
Research program
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Melanoma
Pigment cell cancer
Scottish Terrier
Melanoma
Speciality Oncology
Description : Highly aggressive cancer occurring on the skin surface, in the eye and mucous membranous sites
Symptoms : -
Age of onset : -
Examination : Histological or cytological analyses
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. André (CNRS of Rennes, France)
Contact : cani-dna@univ-rennes1.fr mageane@antagene.com
Comment : -
Programme de recherche
Research program
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Melanoma
Pigment cell cancer
Scottish Terrier
Melanoma
Speciality Oncology
Description : Highly aggressive cancer occurring on the skin surface, in the eye and mucous membranous sites
Symptoms : -
Age of onset : -
Examination : Histological or cytological analyses
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. André (CNRS of Rennes, France)
Contact : cani-dna@univ-rennes1.fr mageane@antagene.com
Comment : -