ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
Bone proliferation
Description: Non-cancerous proliferating disease altering form and function of the bones of the skull and jaw bone
Symptoms : During the bony proliferation phase, difficulties in chewing, swelling and thickening of the jaw, pain, recurrent fever
Age of onset : Between 4 and 7 months old
Frequency : Not available
Gene involved : SLC37A2
Tested mutation : c.1332C>T
Transmission : Autosomal Dominant with incomplete penetrance
Patent : -
Notes : Because of incomplete penetrance and varying expressivity, many of the dogs carrying the CMO mutation will live without showing clinical signs
Severe bleeding disorder
Description: Lack of von Willebrand factor synthesis, a protein involved in blood coagulation
Symptoms : Important or severe bleeding disorders, difficult to contain, leading to death
Age of onset : From birth
Frequency : 15%
Gene involved : VWF
Tested mutation : c.264delC
Transmission : Autosomal Recessive
Patent : _
Notes : _
Intensity of the red coat pigment
Description: Lightening of the red pigment (phaeomelanin)
Symptoms : Silver, light fawn, cream, white coat... depending on breeds
Age of onset : From birth
Frequency : -
Gene involved : MFSD12
Tested mutation : c.151C>T
Transmission : Autosomal Recessive
Patent : -
Notes : -
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten
ANTAGENE produces an unique genetic fingerprint of a dog or a cat
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Pigment cell cancer
Speciality Oncology
Description : Highly aggressive cancer occurring on the skin surface, in the eye and mucous membranous sites
Symptoms : -
Age of onset : -
Examination : Histological or cytological analyses
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. André (CNRS of Rennes, France)
Contact : cani-dna@univ-rennes1.fr mageane@antagene.com
Comment : -
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Pigment cell cancer
Speciality Oncology
Description : Highly aggressive cancer occurring on the skin surface, in the eye and mucous membranous sites
Symptoms : -
Age of onset : -
Examination : Histological or cytological analyses
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. André (CNRS of Rennes, France)
Contact : cani-dna@univ-rennes1.fr mageane@antagene.com
Comment : -