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New English Bulldog
New English Bulldog
55€
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Antagene Parenté
DNA - Certified parentage
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten
75€ (Except SH and OPTIGEN tests)
Antagene Séléction
DNA - based testing for hereditary diseases
ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
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HUU - Hyperuricosuria
Predisposition to urate bladder stones
New English Bulldog
HUU - Hyperuricosuria
Description: Metabolic disorder resulting in elevated levels of uric acid in blood and urine. This trait predisposes dogs to form urate bladder stones
Symptoms : Difficulty urinating, blood in urine, urinary incontinence, abdominal pain. Some complications are possible: acute kidney failure, urinary tract infection, or rupture of bladder
Age of onset : Between 3 and 6 years old
Frequency :
Gene involved : SLC2A9
Tested mutation : c.616G>T
Transmission : Autosomal Recessive
Patent : _
Notes : Predisposition to urate bladder stones caused by this mutation is variable according to breeds. Most of homozygous mutated dogs never show symptoms.
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CMR1 - Multifocal Retinopathy
Retinal detachments
New English Bulldog
CMR1 - Multifocal Retinopathy
Description: Retinal pigment epithelial dysplasia causing localized multifocal retinal detachments
Symptoms : In the mild form, no vision disorders are reported despite the abnormal retina. In the severe form, lesions can lead to blindness
Age of onset : Before 4 months old
Frequency : Not available
Gene involved : BEST1
Tested mutation : c.73C>T
Transmission : Autosomal Recessive
Patent : _
Notes : _
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DM - Degenerative Myelopathy
Progressive paralysis
New English Bulldog
DM - Degenerative Myelopathy
Description: Degenerative disease of the spinal cord causing progressive paralysis
Symptoms : Loss of coordination (ataxia) in the hind limbs until paraplegia, loss of urinary and fecal continence. If signs progress for a longer period of time, eventually weakness will develop in the front limbs.
Age of onset : Between 8 and 14 years old
Frequency : _
Gene involved : SOD1
Tested mutation : c.118G>A
Transmission : Autosomal Recessive
Patent : _
Notes :
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MERLE - Merle Coat Colour
M locus
New English Bulldog
MERLE - Merle Coat Colour
Description: DNA test can identify dogs carrying the genotype "Merle" (M Locus) and highlight double merles and cryptic merles
Symptoms : Patches of diluted pigment intermingled with normal melanin, blue eyes, often associated with a wide range of auditory and ophthalmologic abnormalities. Double merles are predominantly white
Age of onset : From birth
Frequency : Not available
Gene involved : SILV
Tested mutation : SINE insertion
Transmission : Autosomal Dominant
Patent : -
Notes :
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