Malinois

Malinois

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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SDCA1 - Spongy Degeneration with Cerebellar Ataxia

Nervous system degeneration

Malinois

SDCA1 - Spongy Degeneration with Cerebellar Ataxia

Nervous system degeneration

Description: Cerebellar dysfunction

Symptoms : Wide-based ataxic gait (more obvious in the hind limbs), exagerated gait movements, seizures, run into obstacles. Rapid and severe progression of clinical signs. Less consistent: stumbling, staggering, intention tremor, bunny hopping, balance loss, falling and decelerated eye ball coordination during fast head motion. Muscle spasms and aggravation of cerebellar symptoms after stress or exercise

Age of onset : Between 4 and 9 weeks old

Frequency : Not available

Gene involved : KCNJ10

Tested mutation : c.986T>C

Transmission : Autosomal Recessive

Patent : -

Notes :

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SDCA2 - Spongy Degeneration with Cerebellar Ataxia

Nervous system degeneration

Malinois

SDCA2 - Spongy Degeneration with Cerebellar Ataxia

Nervous system degeneration

Description: Cerebellar dysfunction

Symptoms : Generalized ataxic gait, pacing, circling, inability to ambulate, seizures, central blindness. Rapid and severe progression of clinical signs.

Age of onset : Between 4 and 6 weeks old

Frequency : 16% carriers

Gene involved : ATP1B2

Tested mutation : c.130_131ins227

Transmission : Autosomal Recessive

Patent : -

Notes :

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DM - Degenerative Myelopathy

Progressive paralysis

Malinois

DM - Degenerative Myelopathy

Progressive paralysis

Description: Degenerative disease of the spinal cord causing progressive paralysis

Symptoms : Loss of coordination (ataxia) in the hind limbs until paraplegia, loss of urinary and fecal continence. If signs progress for a longer period of time, eventually weakness will develop in the front limbs.

Age of onset : Between 8 and 14 years old

Frequency : _

Gene involved : SOD1

Tested mutation : c.118G>A

Transmission : Autosomal Recessive

Patent : _

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DIL - Dilution (D Locus)

Lighter black or brown coat colour

Malinois

DIL - Dilution (D Locus)

Lighter black or brown coat colour

Description: DNA test can identifying dogs carrying the genotype "Dilute" (D Locus)

Symptoms : Dilution or lightening effect of the black or brown colours

Age of onset : From birth

Frequency : _

Gene involved : MLPH

Tested mutation : c.-22G>A

Transmission : Autosomal Recessive

Patent : _

Notes : _

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INT - I Locus

Intensity of the red coat pigment

Malinois

INT - I Locus

Intensity of the red coat pigment

Description: Lightening of the red pigment (phaeomelanin)

Symptoms : Silver, light fawn, cream, white coat... depending on breeds

Age of onset : From birth

Frequency : -

Gene involved : MFSD12

Tested mutation : c.151C>T

Transmission : Autosomal Recessive

Patent : -

Notes : -

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PL - Hair Length

Long coat / Short coat

Malinois

PL - Hair Length

Long coat / Short coat

Description: DNA test can identifying dogs carrying the genotype "Long Coat"

Symptoms : _

Age of onset : _

Frequency : -

Gene involved : FGF5

Tested mutation : c.284G>T

Transmission : Autosomal Recessive

Patent : _

Notes : _

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Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten

45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat