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Landseer
Landseer
Antagene Séléction
DNA - based testing for hereditary diseases
ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
CYST - Cystinuria
Kidney stones
Landseer
CYST - Cystinuria
Description: Accumulation of cystine in kidney, which may further precipitate to form calculi (stones) and inflammation of the system
Symptoms : Difficulties to urinate, there may be blood in urine. Untreated, this disease can lead to kidney failure and death of the dog
Age of onset : From the age of 6 months
Frequency : 26%
Gene involved : SLC3A1
Tested mutation : c.586C>T
Transmission : Autosomal Recessive
Patent : _
Notes : _
DM - Degenerative Myelopathy
Progressive paralysis
Landseer
DM - Degenerative Myelopathy
Description: Degenerative disease of the spinal cord causing progressive paralysis
Symptoms : Loss of coordination (ataxia) in the hind limbs until paraplegia, loss of urinary and fecal continence. If signs progress for a longer period of time, eventually weakness will develop in the front limbs.
Age of onset : Between 8 and 14 years old
Frequency : _
Gene involved : SOD1
Tested mutation : c.118G>A
Transmission : Autosomal Recessive
Patent : _
Notes :
TP-A - Thrombopathia
Bleeding disorder
Landseer
TP-A - Thrombopathia
Description: Abnormal platelet function preventing normal clotting
Symptoms : Recurrent nose bleeds, excessive bleeding of the gums, bruises, hematomas, internal bleeding, bloody or dark tarry feces, lameness
Age of onset : From birth
Frequency : Not available
Gene involved : RASGRP2
Tested mutation : c.982C>T
Transmission : Autosomal Recessive
Patent : -
Notes :
Antagene Identité
Genetic Identification
ANTAGENE produces an unique genetic fingerprint of a dog or a cat
Antagene Parenté
DNA - Certified parentage
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten