ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
Early muscular atrophy
Description: Atrophy of muscle fibres due to myofibres remodelling
Symptoms : Muscle weakness, exercise intolerance. Onset of progressive weight loss by 15 days old
Age of onset : Between 2 and 5 months old
Frequency : Lower than 5% carriers
Gene involved : PTPLA
Tested mutation : c.191_192ins236b
Transmission : Autosomal Recessive
Patent : _
Notes : For more information: www.labradorcnm.com
Dwarfism
Description: Abnormality of skeletal development leading to mild disproportionate dwarfism
Symptoms : Short legs with normal body length and width, lower shoulder height (< 50 cm) compared to the international breed standard (54-57 cm), not affecting health condition
Age of onset : -
Frequency : Not available
Gene involved : COL11A2
Tested mutation : c.143G>C
Transmission : Autosomal Recessive
Patent : -
Notes :
Progressive loss of vision
Description: Progressive rod-cone degeneration
Symptoms : Declining vision (at night and then in daylight) and eventual blindness
Age of onset : Between 1,5 and 6 years old
Frequency : 23% carriers in European population
Gene involved : PRCD
Tested mutation : c.5G>A
Transmission : Autosomal Recessive
Patent : _
Notes : _
Presence of brown or yellow coat
Description: DNA test can identifying dogs carrying the genotype "Brown" (Locus B) and the genotype "Yellow" (E Locus)
Symptoms : _
Age of onset : _
Frequency : _
Gene involved : TYRP1 and MC1R
Tested mutation : TYRP1: S41C, Q331X and 345delP MC1R: R306X
Transmission : Autosomal
Patent : _
Notes : _
Long coat / Short coat
Description: DNA test can identifying dogs carrying the genotype "Long Coat"
Symptoms : -
Age of onset : -
Frequency : -
Gene involved : FGF5
Tested mutation : c.284G>T
Transmission : Autosomal Recessive
Patent : -
Notes : -
Lighter coat colour
Description: DNA test can identifying dogs carrying the genotype "Dilute" (D Locus)
Symptoms : Dilution or lightening effect of the solid colours
Age of onset : From birth
Frequency : _
Gene involved : MLPH
Tested mutation : c.-22G>A
Transmission : Autosomal Recessive
Patent : _
Notes : _
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten
ANTAGENE produces an unique genetic fingerprint of a dog or a cat
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Pigment cell cancer
Speciality Oncology
Description : Highly aggressive cancer occurring on the skin surface, in the eye and mucous membranous sites
Symptoms : -
Age of onset : -
Examination : Histological or cytological analyses
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. André (CNRS of Rennes, France)
Contact : cani-dna@univ-rennes1.fr mageane@antagene.com
Comment : -
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Pigment cell cancer
Speciality Oncology
Description : Highly aggressive cancer occurring on the skin surface, in the eye and mucous membranous sites
Symptoms : -
Age of onset : -
Examination : Histological or cytological analyses
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. André (CNRS of Rennes, France)
Contact : cani-dna@univ-rennes1.fr mageane@antagene.com
Comment : -