ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
Progressive loss of vision
Description: Rod and cone dysplasia type 1
Symptoms : Progressive loss of vision (at night and then in daylight) culminating in blindness
Age of onset : Between 1 and 12 months old
Frequency : 7,5% carriers in American population
Gene involved : PDE6B
Tested mutation : c.2420G>A
Transmission : Autosomal Recessive
Patent : _
Notes : Another DNA test (PRA-rcd4) is available to detect another form of PRA in this breed.
Fatal immunodeficiency disease
Description: Abnormal immune system resulting in a malfunction of the defence mechanism
Symptoms : High fevers, severe and recurrent infections leading to death
Age of onset : From birth
Frequency : 12%
Gene involved : ITGB-2
Tested mutation : c.107G>C
Transmission : Autosomal Recessive
Patent : _
Notes : _
Progressive loss of vision
Description: Rod and cone dysplasia type 4
Symptoms : Progressive loss of vision (at night and then in daylight) culminating in blindness
Age of onset : Average age of 10 years, cases observed from 5 to 12 years old
Frequency : World population: 49% carriers ; French population: 27% carriers
Gene involved : C2orf71
Tested mutation : c.3149_3150insC
Transmission : Autosomal Recessive
Patent :
Notes : This mutation accounts for 70% of PRA cases in the Irish Setter breed. Another DNA test (PRA-rcd1) is available to detect another form of PRA in this breed.
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten
ANTAGENE produces an unique genetic fingerprint of a dog or a cat