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Great Dane
Great Dane
Antagene Séléction
DNA - based testing for hereditary diseases
ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
DIL - Dilution (D Locus)
Lighter black or brown coat colour
Great Dane
DIL - Dilution (D Locus)
Description: DNA test can identifying dogs carrying the genotype "Dilute" (D Locus)
Symptoms : Dilution or lightening effect of the black or brown colours
Age of onset : From birth
Frequency : _
Gene involved : MLPH
Tested mutation : c.-22G>A
Transmission : Autosomal Recessive
Patent : _
Notes : _
Antagene Parenté
DNA - Certified parentage
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten
Antagene Identité
Genetic Identification
ANTAGENE produces an unique genetic fingerprint of a dog or a cat
Programme de recherche
Research program
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
DCM - Dilated Cardiomyopathy
Cardiac muscle degeneration
Great Dane
DCM - Dilated Cardiomyopathy
Speciality Cardiology
Description : Myocardial degeneration resulting in a dilation of cardiac cavities and a thinning of the cardiac walls
Symptoms : Exercise intolerance, weight loss, cough, respiratory difficulties, abdominal distension, muscular weakness, loss of consciousness, syncope, sudden death
Age of onset : -
Examination : Echocardiography, Doppler, electrocardiography and/or radiography
Progress : Undergoing sampling. This project has been studied within the framework of the LUPA European project. A first dog cohort allowed to underline few regions of the canine genome linked to the disease. These regions include several candidate genes currently i
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : LUPA www.eurolupa.org, Uppsala University (Sweden)
Contact : mageane@antagene.com
Comment : -
Coxofemoral Dysplasia
Hip dysplasia
Great Dane
Coxofemoral Dysplasia
Speciality Orthopaedics
Description : Developmental disorder of hip resulting in a joint instability
Symptoms : Arthrosis, gait problems unrelated to the degree of dysplasia
Age of onset : -
Examination : Radiography
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. André (CNRS of Rennes, France)
Contact : cani-dna@univ-rennes1.fr mageane@antagene.com
Comment : -
Programme de recherche
Research program
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
DCM - Dilated Cardiomyopathy
Cardiac muscle degeneration
Great Dane
DCM - Dilated Cardiomyopathy
Speciality Cardiology
Description : Myocardial degeneration resulting in a dilation of cardiac cavities and a thinning of the cardiac walls
Symptoms : Exercise intolerance, weight loss, cough, respiratory difficulties, abdominal distension, muscular weakness, loss of consciousness, syncope, sudden death
Age of onset : -
Examination : Echocardiography, Doppler, electrocardiography and/or radiography
Progress : `
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : LUPA www.eurolupa.org, Uppsala University (Sweden)
Contact : mageane@antagene.com
Comment : -
Coxofemoral Dysplasia
Hip dysplasia
Great Dane
Coxofemoral Dysplasia
Speciality Orthopaedics
Description : Developmental disorder of hip resulting in a joint instability
Symptoms : Arthrosis, gait problems unrelated to the degree of dysplasia
Age of onset : -
Examination : Radiography
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. André (CNRS of Rennes, France)
Contact : cani-dna@univ-rennes1.fr mageane@antagene.com
Comment : -