ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
Lesions on distal extremities caused by self-mutilation
Description: Self-mutilation of limb extremities linked with located insensivity to pain
Symptoms : Lesions on distal extremities caused by self-mutilation, loss of sensivity to pain on distal limbs, tendency to lick or bite their own pads resulting in auto-amputation of claws, digits and footpads in severe cases, no limping
Age of onset : From 3 to 12 months
Frequency : Not available
Gene involved :
Tested mutation :
Transmission : Autosomal Recessive
Patent :
Notes : This DNA test is the result of researches and efforts to improve the health and to determine the risk for purebreed dogs to develop Acral Mutilation Syndrome. The team "Canine Genetics" from CNRS-Université de Rennes I led the research that allowed the development of this risk test. Only Antagene masters the performing process of this DNA test.
Loss of daylight vision
Description: Degeneration of the retinal cones
Symptoms : Day-blindness and photophobia
Age of onset : Between 8 and 12 weeks old
Frequency : 14% carriers in American population
Gene involved : CNGB3
Tested mutation : c.784G>A
Transmission : Autosomal Recessive
Patent : _
Notes : _
Moderate to severe bleeding disorder
Description: Low level and abnormal function of von Willebrand factor, a protein involved in blood coagulation
Symptoms : Important bleedings or haemorrhagic episodes, potentially lethal, excessive gingival haemorrhage during eruption of adult teeth, nose bleeding, skin bruising, prolonged bleeding after surgery or trauma
Age of onset : From birth
Frequency : Not available
Gene involved : VWF
Tested mutation : A>G in a2 domain
Transmission : Autosomal Recessive
Patent : -
Notes :
Cutaneous lesions
Description: Blistering disorder of the skin and mucous membranes in which separation of epidermis from the underlying dermis occurring
Symptoms : Skin blistering and erosions primarily affecting the footpads, pressure points on the legs, medial aspect of the ears, and on the gingivae, lips, and tongue, growth retardation, nails drop
Age of onset : From the age of 2 months
Frequency : Not available
Gene involved : LAMA3
Tested mutation : c.1514C>T
Transmission : Autosomal Recessive
Patent : -
Notes :
ANTAGENE produces an unique genetic fingerprint of a dog or a cat
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten