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French Mastiff
French Mastiff
Antagene Séléction
DNA - based testing for hereditary diseases
ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
CMR1 - Multifocal Retinopathy
Retinal detachments
French Mastiff
CMR1 - Multifocal Retinopathy
Description: Retinal pigment epithelial dysplasia causing localized multifocal retinal detachments
Symptoms : In the mild form, no vision disorders are reported despite the abnormal retina. In the severe form, lesions can lead to blindness
Age of onset : Before 4 months old
Frequency : Not available
Gene involved : BEST1
Tested mutation : c.73C>T
Transmission : Autosomal Recessive
Patent : _
Notes : _
HFH-B - Hereditary Footpad Hyperkeratosis
Corny Feet
French Mastiff
HFH-B - Hereditary Footpad Hyperkeratosis
Description: Thickening and hardening of footpads resulting from abnormal proliferation of epidermal cells.
Symptoms : Horny protrusions on all footpads, fissures and cracks possibly causing great pain and therefore reduced mobility of the dog.
Age of onset : Between 4 and 9 months old
Frequency : 11% carriers in French population
Gene involved :
Tested mutation :
Transmission : Autosomal Recessive
Patent :
Notes : The research was led by the team of Dr. Catherine André (CNRS of Rennes, France) in collaboration with Antagene.
Antagene Parenté
DNA - Certified parentage
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten
Antagene Identité
Genetic Identification
ANTAGENE produces an unique genetic fingerprint of a dog or a cat
Programme de recherche
Research program
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Coxofemoral Dysplasia
Hip dysplasia
French Mastiff
Coxofemoral Dysplasia
Speciality Orthopaedics
Description : Developmental disorder of hip resulting in a joint instability
Symptoms : Arthrosis, gait problems unrelated to the degree of dysplasia
Age of onset : -
Examination : Radiography
Progress : Undergoing sampling
Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)
Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree
Collaboration : Dr C. André (CNRS of Rennes, France)
Contact : cani-dna@univ-rennes1.frmageane@antagene.com
Comment : -