ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
Brain disease
Description: Abnormal development and structure of the cerebellum
Symptoms : Non-progressive mild to moderate cerebellar ataxia (truncal sway, subtly uncoordinated gait to episodic rolling or falling), reduced or absent menace reflex. Some dogs may have epileptic seizures, tremors, proprioceptive deficits, nystagmus (abnormal eye movement), strabismus
Age of onset : From a few weeks old
Frequency : 16% carriers
Gene involved : VLDLR
Tested mutation : c.1713delC
Transmission : Autosomal Recessive
Patent : -
Notes :
Progressive paralysis
Description: Degenerative disease of the spinal cord causing progressive paralysis
Symptoms : Loss of coordination (ataxia) in the hind limbs until paraplegia, loss of urinary and fecal continence. If signs progress for a longer period of time, eventually weakness will develop in the front limbs.
Age of onset : Between 8 and 14 years old
Frequency : _
Gene involved : SOD1
Tested mutation : c.118G>A
Transmission : Autosomal Recessive
Patent : _
Notes :
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