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American Hairless Terrier
American Hairless Terrier
Antagene Séléction
DNA - based testing for hereditary diseases
ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
PLL-A - Primary Lens Luxation
Lens displacement in the eye
American Hairless Terrier
PLL-A - Primary Lens Luxation
Description: Partial or complete breakdown of the zonular ligaments suspending the lens
Symptoms : Reddened eye, pain, corneal oedema, glaucoma which can damage the optic nerve causing blindness
Age of onset : Between 3 and 8 years old
Frequency : Not available
Gene involved : ADAMTS17
Tested mutation : c.1473+1G>A
Transmission : Autosomal Recessive
Patent : _
Notes : Primary lens luxation affects both eyes although few weeks or few months can separate luxation from each eye.
DM - Degenerative Myelopathy
Progressive paralysis
American Hairless Terrier
DM - Degenerative Myelopathy
Description: Degenerative disease of the spinal cord causing progressive paralysis
Symptoms : Loss of coordination (ataxia) in the hind limbs until paraplegia, loss of urinary and fecal continence. If signs progress for a longer period of time, eventually weakness will develop in the front limbs.
Age of onset : Between 8 and 14 years old
Frequency : _
Gene involved : SOD1
Tested mutation : c.118G>A
Transmission : Autosomal Recessive
Patent : _
Notes :
VWD1 - von Willebrand's Disease Type I
Mild bleeding disorder
American Hairless Terrier
VWD1 - von Willebrand's Disease Type I
Description: Insufficient synthesis of von Willebrand factor, a protein involved in blood coagulation
Symptoms : Important bleedings or haemorrhagic episodes, potentially lethal only after a surgical act or trauma. Spontaneous bleedings of mucous membranes observed in very rare cases
Age of onset : From birth
Frequency : Not available
Gene involved : VWF
Tested mutation : c.7142C>T
Transmission : Autosomal Recessive
Patent : _
Notes : Attenuate symptoms can exceptionally be observed in heterozygous dogs
PRA-prcd - Progressive Retinal Atrophy (Optigen payment 130$)
Progressive loss of vision
American Hairless Terrier
PRA-prcd - Progressive Retinal Atrophy (Optigen payment 130$)
Description: Progressive rod-cone degeneration
Symptoms : Declining vision (at night and then in daylight) and eventual blindness
Age of onset : Between 2 and 12 years old
Frequency : Not available
Gene involved : PRCD
Tested mutation : c.5G>A
Transmission : Autosomal Recessive
Patent : _
Notes : _
Antagene Parenté
DNA - Certified parentage
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten
Antagene Identité
Genetic Identification
ANTAGENE produces an unique genetic fingerprint of a dog or a cat