ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
Progressive loss of vision
Description: Progressive rod-cone degeneration
Symptoms : Progressive loss of vision (at night and then in daylight) culminating in blindness
Age of onset : Between 1 and 2 years old
Frequency : Not available
Gene involved : CEP290
Tested mutation : IVS50 + 9T>G
Transmission : Autosomal Recessive
Patent : _
Notes : _
Hemolytic anaemia
Description: Lack of the pyruvate kinase enzyme causing an early destruction of red blood cells, leading to an anaemia more or less severe according to individuals
Symptoms : Lethargy, diarrhea, pale mucous membranes, lack of appetite, weight loss, icterus
Age of onset : Variable. Some rare cases declare an early severe form. Anaemia may only be moderate and intermittently detectable. In mild cases, symptoms may be late onset.
Frequency : 42% carriers in the studied population (USA and UK)
Gene involved : PKLR
Tested mutation : c.693+304G>A
Transmission : Autosomal Recessive
Patent :
Notes :
Episodic muscle weakness
Description: Episodes of low serum potassium levels leading to muscle damages
Symptoms : Episodic muscle weakness, muscle pain, ventroflexion of the head and neck, locomotor difficulties
Age of onset : Between 2 and 10 months old
Frequency : Not available
Gene involved : WNK4
Tested mutation : c.2899C>T
Transmission : Autosomal Recessive
Patent : -
Notes :
ANTAGENE produces an unique genetic fingerprint of a dog or a cat
ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten