CEA - Collie Eye Anomaly (Choroidal Hypoplasia - partner laboratory 90€)/Générique

Loss of vision

Description: 
Abnormal development of the choroid (a layer of tissue under the retina of the eye)
Symptomes: 
Variability of clinical signs according to the breed and individuals: - grade 1 and 2: mild form, without disablement and evolution - grade 3 and 4: severe form with retinal detachment and intraocular haemorrhage, might cause blindness
Age d'aparition: 
From the age of 8 weeks
Fréquence: 
Not available
Gène impliqué: 
NHEJ1
Mutation testée: 
c.588+462_588+8260del7799bp
Transmission: 
Autosomal Recessive
Brevet: 
_
Remarques: 
Mild and severe forms being due to a single mutation in the same gene, dogs with a mild form may produce offspring presenting a severe form.