The
progressive retinal atrophy(PRA) refers to a group of diseases that cause the retina of the eye to degenerate slowly over time. The result is declining vision and progressive blindness. The disease might develop at different ages or with differing severity from one breed to another.
The progressive retinal atrophy is inherited as an autosomal recessive way but there are some PRA closely linked to the X-Chromosom and dominant PRA.
ANTAGENE proposes a DNA test to detect the progressive retinal atrophy in following breeds :
• Corgi
• Irish Setter (pde6b form)
• Sloughi (pde6b form)
• Mastiff (dominant rho form)
• German Pointer (cngb3 form)
• Husky (rpgr form linked to the X-Chromosom)
• Samoyede (rpgr form linked to the X-Chromosom)
The frequency of carrier dogs in these breeds is about 1% and 5%.
In partnership with the laboratory OPTIGEN (USA), ANTAGENE proposes also a DNA test to detect the prcd form of the progressive retinal atrophy (prcd-PRA) in the following breeds :
• Labrador Retriever
• Miniature poodle
• English and American Cocker Spaniel
To test your dog for prcd-PRA, please feel free to contact us. Further information about Optigen : www.optigen.com
Why to test your dog ?
• to detect very early carrier dog
• to select breeding animals and to adapt breeding strategies
• to avoid producing and selling pups affected by
• to anticipate the apparition of the disease
