Familial Nephropathy



Familial Nephropathy in English Cocker Spaniel

The Familial Nephropathy is a juvenile-onset fatal kidney disease. Dogs typically develop chronic renal failure from 6 months of age, often leading to death before 2 years of age. Current genetic data on european English Cocker Spaniel population indicates a frequency of at least 20 % of dogs carrying the genetic anomaly responsible for this autosomal recessive genetic disease.

This new genetic test allows precocious diagnosis of this disease, before manifestation of the first clinical signs. Thanks to this test, breeders will be able to detect very early carrier puppies, to select breeding animals and to adapt breeding strategies in order to avoid producing and selling puppies affected by Familial Nephropathy.

Gene and mutation causing Familial Nephropathy in the English Cocker Spaniel have been discovered by the team of Pr Keith Murphy from Texas A&M University. ANTAGENE has an exclusive license for Europe from MERLOGEN LLC (USA) for Familial Nephropathy testing in dog.


 Familial Nephropathy.pdf 64.39 KB 30.01.2008






 
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