Research program

Description: 
ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests
Tests: 

Spinning

Title:
Spinning
Status:
Active
Description: 
Disease classified as an obsessive compulsive disorder. Current hypothesis: syndrome suggested to resemble partial seizures (without loss of consciousness) during which an abnormal electrical activity occurs in the temporal lobe of the brain (brain area involved in behaviour).
Symptomes: 
Affected dogs spin rapidly in tight circles, more or less frequently, with or without apparent interest in the tail. Some cases may be associated with aggressiveness which is triggered without reason and/or growling against a person or an object, irrational fears or disorders of consciousness with an apparent disassociation of the environment (trance-like behaviour, hallucinatory fly-catching compulsions...).
Age d'aparition: 
Puppies can be affected as early as few months, but the hormonal changes at puberty appear to be involved in the onset or worsening of this disorder.
Examen: 
Neurological check-up
Avancement: 
Undergoing sampling. The first genetic results would show a genetically complex disorder.
Collaboration: 
Dr C. Escriou (VetAgro Sup, France), veterinary neurologist and team of Dr H. Lohi (University of Helsinki, Finland)
Contact: 
spinning@vetagro-sup.fr mageane@antagene.com
Remarques: 
Your involvement in research is essential to our progress.
Spécialité: 
Neurology
Prélèvements pour participer à la recherche: 
Blood sample in EDTA tube (2-4 mL)
Documents à joindre aux prélèvements: 
Clinical certificate, Sampling certificate, Copy of pedigree
Accroche: 
Tail chasing
Race liée: 
Bull Terrier