PKD - Polycystic Kidney Disease/British Shorthair

Kidney failure

Description: 
Cysts compressing the renal tissue and preventing a correct kidney functioning
Symptomes: 
Excessive water consumption, excessive urine volume, weight loss, vomiting, lethargy, chronic and ultimately fatal renal failure
Age d'aparition: 
Between 2 and 10 years old
Fréquence: 
The initial study showed 12% carriers. Currently, the frequency is 1% carriers in the tested population
Gène impliqué: 
PKD1
Mutation testée: 
C.10063C>A
Transmission: 
Autosomal Dominant
Brevet: 
_
Remarques: 
The study of PKD mutation frequency shows a significant decrease since 2006 in the tested population.