NCL-A - Cerebellar Ataxia/American Bully

Race liée: 

Nervous system degeneration

Description: 
Cerebellum degeneration with neuronal ceroid lipofuscinosis leading to nervous system disorders.
Symptomes: 
"Wobbly" gait, tremors, incoordination, loss of balance. At the final stage, the dog is unable to move and euthanasia is generally practiced
Age d'aparition: 
Between 3 and 5 years old
Fréquence: 
Not available
Gène impliqué: 
ARSG
Mutation testée: 
c.296G>A
Transmission: 
Autosomal Recessive
Brevet: 
ANTAGENE Worldwide License
Remarques: 
The tested mutation is specific to cerebellar ataxia in American Staffordshire Terrier but may be present in American Bully given its origins. An another DNA test (NCL-E) is available to detect an other form of ataxia in this breed.