NAH - Pituitary Dwarfism/générique

Growth retardation

Description: 
Underdevelopment of the pituitary gland leading to pituitary hormone deficiency causing growth retardation
Symptomes: 
Marked growth retardation, small size, retention of puppy coat, lack of adult coat, bilateral symetrical loss of hair coat mostly located at the trunk, the neck and at the top of the legs Less frequent signs : hyperpigmentation of the skin, scales, bacterial infections
Age d'aparition: 
Significated clinical signs 2-3 months after birth
Fréquence: 
-
Gène impliqué: 
LHX3
Mutation testée: 
7bp del intron 5 affects splice site
Transmission: 
Autosomal Recessive
Brevet: 
-