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HUU - Hyperuricosuria/Bulldog

Predisposition to urate bladder stones

Description: 
Metabolic disorder resulting in elevated levels of uric acid in blood and urine. This trait predisposes dogs to form urate bladder stones
Symptomes: 
Difficulty urinating, blood in urine, urinary incontinence, abdominal pain. Some complications are possible: acute kidney failure, urinary tract infection, or rupture of bladder
Age d'aparition: 
Between 3 and 6 years old
Fréquence: 
35%
Gène impliqué: 
SLC2A9
Mutation testée: 
c.616G>T
Transmission: 
Autosomal Recessive
Brevet: 
_
Remarques: 
Predisposition to urate bladder stones caused by this mutation is variable according to breeds. Most of homozygous mutated dogs never show symptoms.