Welsh Corgi Cardigan

PRA-rcd3 - Progressive Retinal Atrophy

Progressive loss of vision

Description: Rod and cone dysplasia type 3

Symptoms : Progressive loss of vision (at night and then in daylight) culminating in blindness

Age of onset : Between 6 months and 3 years old

Frequency : 8,5% carriers in American population

Gene involved : PDE6A

Tested mutation : c.1940delA

Transmission : Autosomal Recessive

Patent : _

Notes : _

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Welsh Corgi Cardigan

DM - Degenerative Myelopathy

Progressive paralysis

Description: Degenerative disease of the spinal cord causing progressive paralysis

Symptoms : Loss of coordination (ataxia) in the hind limbs until paraplegia, loss of urinary and fecal continence. If signs progress for a longer period of time, eventually weakness will develop in the front limbs.

Age of onset : Between 8 and 14 years old

Frequency : _

Gene involved : SOD1

Tested mutation : c.118G>A

Transmission : Autosomal Recessive

Patent : _

Notes :

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Welsh Corgi Cardigan

PL - Hair Length

Long coat / Short coat

Description: DNA test can identifying dogs carrying the genotype "Long Coat"

Symptoms : _

Age of onset : _

Frequency : -

Gene involved : FGF5

Tested mutation : c.284G>T

Transmission : Autosomal Recessive

Patent : _

Notes : _

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Welsh Corgi Cardigan

MERLE - Merle Coat Colour

M locus

Description: DNA test can identify dogs carrying the genotype "Merle" (M Locus) and highlight double merles and cryptic merles

Symptoms : Patches of diluted pigment intermingled with normal melanin, blue eyes, often associated with a wide range of auditory and ophthalmologic abnormalities. Double merles are predominantly white

Age of onset : From birth

Frequency : Not available

Gene involved : SILV

Tested mutation : SINE insertion

Transmission : Autosomal Dominant

Patent : -

Notes :

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