Weimaraner

Weimaraner

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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HUU - Hyperuricosuria

Predisposition to urate bladder stones

Weimaraner

HUU - Hyperuricosuria

Predisposition to urate bladder stones

Description: Metabolic disorder resulting in elevated levels of uric acid in blood and urine. This trait predisposes dogs to form urate bladder stones

Symptoms : Difficulty urinating, blood in urine, urinary incontinence, abdominal pain. Some complications are possible: acute kidney failure, urinary tract infection, or rupture of bladder

Age of onset : Between 3 and 6 years old

Frequency : 35%

Gene involved : SLC2A9

Tested mutation : c.616G>T

Transmission : Autosomal Recessive

Patent : _

Notes : Predisposition to urate bladder stones caused by this mutation is variable according to breeds. Most of homozygous mutated dogs never show symptoms.

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SD - Spinal Dysraphism

Motor function disorder of the hind limbs

Weimaraner

SD - Spinal Dysraphism

Motor function disorder of the hind limbs

Description: Spinal chord malformation resulting in motor function disorder of the hind limbs

Symptoms : Regarding the hind limbs only, motor function disorder, loss of balance and coordination, proprioceptive deficits. Specific symptoms: symmetric ‘‘bunny-hopping’’ or simultaneous use of the pelvic limbs. Bilateral withdrawal reflex (pinching one paw elicits flexion of both hind limbs)

Age of onset : As soon as the puppy starts walking

Frequency : 9% carriers in French population

Gene involved : NKX2-8

Tested mutation : c.174del_G;ins2bp(AA)

Transmission : Autosomal Recessive

Patent : -

Notes :

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HYM - Hypomyelination

Tremors

Weimaraner

HYM - Hypomyelination

Tremors

Description: Thickness of the myelin sheath covering the neurons of the spinal cord is below normal

Symptoms : Generalized tremor, "hopping" gait in the hind limbs. Clinical signs diminished with time by 3 to 4 months of age, though some dogs retained a persistent fine tremor of the hind limbs

Age of onset : From 1 to 2 weeks old

Frequency : 9% carriers in American population

Gene involved : FNIP2

Tested mutation : c.880delA

Transmission : Autosomal Recessive

Patent : -

Notes :

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PL - Hair Length

Long coat / Short coat

Weimaraner

PL - Hair Length

Long coat / Short coat

Description: DNA test can identifying dogs carrying the genotype "Long Coat"

Symptoms : _

Age of onset : _

Frequency : -

Gene involved : FGF5

Tested mutation : c.284G>T

Transmission : Autosomal Recessive

Patent : _

Notes : _

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45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat

55€ Order

Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten