ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
Hemolytic anaemia
Description: Lack of the pyruvate kinase enzyme causing an early destruction of red blood cells, leading to an anaemia more or less severe according to individuals
Symptoms : Pale mucous membranes, lethargy, exercise intolerance abnormal bone density, liver failure, shortened life expectancy
Age of onset : Between 4 months and 2 years old
Frequency : Not available
Gene involved : PKLR
Tested mutation : c.848T>C
Transmission : Autosomal Recessive
Patent : -
Notes :
Progressive paralysis
Description: Degenerative disease of the spinal cord causing progressive paralysis
Symptoms : Loss of coordination (ataxia) in the hind limbs until paraplegia, loss of urinary and fecal continence. If signs progress for a longer period of time, eventually weakness will develop in the front limbs.
Age of onset : Between 8 and 14 years old
Frequency : _
Gene involved : SOD1
Tested mutation : c.118G>A
Transmission : Autosomal Recessive
Patent : _
Notes :
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