Parson Russell Terrier

Parson Russell Terrier

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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HUU - Hyperuricosuria

Predisposition to urate bladder stones

Parson Russell Terrier

HUU - Hyperuricosuria

Predisposition to urate bladder stones

Description: Metabolic disorder resulting in elevated levels of uric acid in blood and urine. This trait predisposes dogs to form urate bladder stones

Symptoms : Difficulty urinating, blood in urine, urinary incontinence, abdominal pain. Some complications are possible: acute kidney failure, urinary tract infection, or rupture of bladder

Age of onset : Between 3 and 6 years old

Frequency :

Gene involved : SLC2A9

Tested mutation : c.616G>T

Transmission : Autosomal Recessive

Patent : _

Notes : Predisposition to urate bladder stones caused by this mutation is variable according to breeds. Most of homozygous mutated dogs never show symptoms.

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PLL-A - Primary Lens Luxation

Lens displacement in the eye

Parson Russell Terrier

PLL-A - Primary Lens Luxation

Lens displacement in the eye

Description: Partial or complete breakdown of the zonular ligaments suspending the lens

Symptoms : Reddened eye, pain, corneal oedema, glaucoma which can damage the optic nerve causing blindness

Age of onset : Between 3 and 8 years old

Frequency : 22%

Gene involved : ADAMTS17

Tested mutation : c.1473+1G>A

Transmission : Autosomal Recessive

Patent : _

Notes : Primary lens luxation affects both eyes although few weeks or few months can separate luxation from each eye.

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SCA - Spinocerebellar Ataxia

Nervous system degeneration

Parson Russell Terrier

SCA - Spinocerebellar Ataxia

Nervous system degeneration

Description: Nervous system degeneration with or without myokymia and seizures

Symptoms : Progressive loss of limb coordination, spastic gait, loss of balance, could be combined with seizures and myokymia (involuntary twitching of the muscles)

Age of onset : Between 2 and 6 months old

Frequency : 17% carriers

Gene involved : KCNJ10

Tested mutation : c.627C>G

Transmission : Autosomal Recessive

Patent : -

Notes : An another DNA test (LOA) is available to detect an other form of ataxia in this breed.

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LOA - Late Onset Ataxia

Nervous system degeneration

Parson Russell Terrier

LOA - Late Onset Ataxia

Nervous system degeneration

Description: Nervous system degeneration

Symptoms : Progressive loss of limb coordination, spastic gait, loss of balance, difficulty in jumping

Age of onset : Between 6 and 12 months old

Frequency : 20% carriers

Gene involved : CAPN1

Tested mutation : c.344G>A

Transmission : Autosomal Recessive

Patent : -

Notes : An another DNA test (SCA) is available to detect an other form of ataxia in this breed

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Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat

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Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten