Jack Russell Terrier

Jack Russell Terrier

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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HUU - Hyperuricosuria

Predisposition to urate bladder stones

Jack Russell Terrier

HUU - Hyperuricosuria

Predisposition to urate bladder stones

Description: Metabolic disorder resulting in elevated levels of uric acid in blood and urine. This trait predisposes dogs to form urate bladder stones

Symptoms : Difficulty urinating, blood in urine, urinary incontinence, abdominal pain. Some complications are possible: acute kidney failure, urinary tract infection, or rupture of bladder

Age of onset : Between 3 and 6 years old

Frequency :

Gene involved : SLC2A9

Tested mutation : c.616G>T

Transmission : Autosomal Recessive

Patent : _

Notes : Predisposition to urate bladder stones caused by this mutation is variable according to breeds. Most of homozygous mutated dogs never show symptoms.

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PLL-A - Primary Lens Luxation

Lens displacement in the eye

Jack Russell Terrier

PLL-A - Primary Lens Luxation

Lens displacement in the eye

Description: Partial or complete breakdown of the zonular ligaments suspending the lens

Symptoms : Reddened eye, pain, corneal oedema, glaucoma which can damage the optic nerve causing blindness

Age of onset : Between 3 and 8 years old

Frequency : 27%

Gene involved : ADAMTS17

Tested mutation : c.1473+1G>A

Transmission : Autosomal Recessive

Patent : _

Notes : Primary lens luxation affects both eyes although few weeks or few months can separate luxation from each eye. Some clinical cases are not associate with the mutation.

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QC - Short Tail

Presence of a naturally shortened tail

Jack Russell Terrier

QC - Short Tail

Presence of a naturally shortened tail

Description: DNA test can identifying dogs carrying the phenotype "Natural Bobtail"

Symptoms : Shortened tail, variability according to individuals: missing tail to 3/4 of tail length

Age of onset : _

Frequency : _

Gene involved : T

Tested mutation : c.295C>G

Transmission : Autosomal Dominant

Patent : _

Notes : _

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SCA - Spinocerebellar Ataxia

Nervous system degeneration

Jack Russell Terrier

SCA - Spinocerebellar Ataxia

Nervous system degeneration

Description: Nervous system degeneration with or without myokymia and seizures

Symptoms : Progressive loss of limb coordination, spastic gait, loss of balance, could be combined with seizures and myokymia (involuntary twitching of the muscles)

Age of onset : Between 2 and 6 months old

Frequency : Lower than 5% carriers

Gene involved : KCNJ10

Tested mutation : c.627C>G

Transmission : Autosomal Recessive

Patent : -

Notes : An another DNA test (LOA) is available to detect an other form of ataxia in this breed.

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LOA - Late Onset Ataxia

Nervous system degeneration

Jack Russell Terrier

LOA - Late Onset Ataxia

Nervous system degeneration

Description: Nervous system degeneration

Symptoms : Progressive loss of limb coordination, spastic gait, loss of balance, difficulty in jumping

Age of onset : Between 6 and 12 months old

Frequency : Lower than 5% carriers

Gene involved : CAPN1

Tested mutation : c.344G>A

Transmission : Autosomal Recessive

Patent : -

Notes : An another DNA test (SCA) is available to detect an other form of ataxia in this breed.

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Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten

45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat

Programme de recherche

Research program

ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests

Spinning

Tail chasing

Jack Russell Terrier

Spinning

Tail chasing

Speciality Neurology

Description : Disease classified as an obsessive compulsive disorder

Symptoms : Affected dogs spin rapidly in tight circles, more or less frequently, with or without apparent interest in the tail.

Age of onset : -

Examination : Neurological check-up

Progress : Undergoing sampling

Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)

Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree

Collaboration : Dr C. Escriou (VetAgro Sup, France), veterinary neurologist

Contact : spinning@vetagro-sup.fr mageane@antagene.com

Comment : -

Programme de recherche

Research program

ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests

Spinning

Tail chasing

Jack Russell Terrier

Spinning

Tail chasing

Speciality Neurology

Description : Disease classified as an obsessive compulsive disorder

Symptoms : Affected dogs spin rapidly in tight circles, more or less frequently, with or without apparent interest in the tail.

Age of onset : -

Examination : Neurological check-up

Progress : Undergoing sampling

Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)

Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree

Collaboration : Dr C. Escriou (VetAgro Sup, France), veterinary neurologist

Contact : spinning@vetagro-sup.fr mageane@antagene.com

Comment : -