Irish Setter

Irish Setter

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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PRA-rcd1 - Progressive Retinal Atrophy

Progressive loss of vision

Irish Setter

PRA-rcd1 - Progressive Retinal Atrophy

Progressive loss of vision

Description: Rod and cone dysplasia type 1

Symptoms : Progressive loss of vision (at night and then in daylight) culminating in blindness

Age of onset : Between 1 and 12 months old

Frequency : 7,5% carriers in American population

Gene involved : PDE6B

Tested mutation : c.2420G>A

Transmission : Autosomal Recessive

Patent : _

Notes : Another DNA test (PRA-rcd4) is available to detect another form of PRA in this breed.

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CLAD - Canine Leukocyte Adhesion Deficiency

Fatal immunodeficiency disease

Irish Setter

CLAD - Canine Leukocyte Adhesion Deficiency

Fatal immunodeficiency disease

Description: Abnormal immune system resulting in a malfunction of the defence mechanism

Symptoms : High fevers, severe and recurrent infections leading to death

Age of onset : From birth

Frequency : 12%

Gene involved : ITGB-2

Tested mutation : c.107G>C

Transmission : Autosomal Recessive

Patent : _

Notes : _

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PRA-rcd4 - Progressive Retinal Atrophy

Progressive loss of vision

Irish Setter

PRA-rcd4 - Progressive Retinal Atrophy

Progressive loss of vision

Description: Rod and cone dysplasia type 4

Symptoms : Progressive loss of vision (at night and then in daylight) culminating in blindness

Age of onset : Average age of 10 years, cases observed from 5 to 12 years old

Frequency : World population: 49% carriers ; French population: 27% carriers

Gene involved : C2orf71

Tested mutation : c.3149_3150insC

Transmission : Autosomal Recessive

Patent :

Notes : This mutation accounts for 70% of PRA cases in the Irish Setter breed. Another DNA test (PRA-rcd1) is available to detect another form of PRA in this breed.

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55€ Order

Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten

45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat