Great Dane

Great Dane

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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DIL - Dilution

Lighter coat colour

Great Dane

DIL - Dilution

Lighter coat colour

Description: DNA test can identifying dogs carrying the genotype "Dilute" (D Locus)

Symptoms : Dilution or lightening effect of the solid colours

Age of onset : From birth

Frequency : _

Gene involved : MLPH

Tested mutation : c.-22G>A

Transmission : Autosomal Recessive

Patent : _

Notes : _

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55€ Order

Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten

45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat

Programme de recherche

Research program

ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests

DCM - Dilated Cardiomyopathy

Cardiac muscle degeneration

Great Dane

DCM - Dilated Cardiomyopathy

Cardiac muscle degeneration

Speciality Cardiology

Description : Myocardial degeneration resulting in a dilation of cardiac cavities and a thinning of the cardiac walls

Symptoms : Exercise intolerance, weight loss, cough, respiratory difficulties, abdominal distension, muscular weakness, loss of consciousness, syncope, sudden death

Age of onset : -

Examination : Echocardiography, Doppler, electrocardiography and/or radiography

Progress : Undergoing sampling. This project has been studied within the framework of the LUPA European project. A first dog cohort allowed to underline few regions of the canine genome linked to the disease. These regions include several candidate genes currently i

Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)

Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree

Collaboration : LUPA www.eurolupa.org, Uppsala University (Sweden)

Contact : mageane@antagene.com

Comment : -

Coxofemoral Dysplasia

Hip dysplasia

Great Dane

Coxofemoral Dysplasia

Hip dysplasia

Speciality Orthopaedics

Description : Developmental disorder of hip resulting in a joint instability

Symptoms : Arthrosis, gait problems unrelated to the degree of dysplasia

Age of onset : -

Examination : Radiography

Progress : Undergoing sampling

Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)

Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree

Collaboration : Dr C. André (CNRS of Rennes, France)

Contact : cani-dna@univ-rennes1.fr mageane@antagene.com

Comment : -

Programme de recherche

Research program

ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests

DCM - Dilated Cardiomyopathy

Cardiac muscle degeneration

Great Dane

DCM - Dilated Cardiomyopathy

Cardiac muscle degeneration

Speciality Cardiology

Description : Myocardial degeneration resulting in a dilation of cardiac cavities and a thinning of the cardiac walls

Symptoms : Exercise intolerance, weight loss, cough, respiratory difficulties, abdominal distension, muscular weakness, loss of consciousness, syncope, sudden death

Age of onset : -

Examination : Echocardiography, Doppler, electrocardiography and/or radiography

Progress : `

Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)

Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree

Collaboration : LUPA www.eurolupa.org, Uppsala University (Sweden)

Contact : mageane@antagene.com

Comment : -

Coxofemoral Dysplasia

Hip dysplasia

Great Dane

Coxofemoral Dysplasia

Hip dysplasia

Speciality Orthopaedics

Description : Developmental disorder of hip resulting in a joint instability

Symptoms : Arthrosis, gait problems unrelated to the degree of dysplasia

Age of onset : -

Examination : Radiography

Progress : Undergoing sampling

Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)

Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree

Collaboration : Dr C. André (CNRS of Rennes, France)

Contact : cani-dna@univ-rennes1.fr mageane@antagene.com

Comment : -