Giant Schnauzer

Giant Schnauzer

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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PRA-prcd - Progressive Retinal Atrophy

Progressive loss of vision

Giant Schnauzer

PRA-prcd - Progressive Retinal Atrophy

Progressive loss of vision

Description: Progressive rod-cone degeneration

Symptoms : Declining vision (at night and then in daylight) and eventual blindness

Age of onset : Between 2 and 12 years old

Frequency : Not available

Gene involved : PRCD

Tested mutation : c.5G>A

Transmission : Autosomal Recessive

Patent : _

Notes : _

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HUU - Hyperuricosuria

Predisposition to urate bladder stones

Giant Schnauzer

HUU - Hyperuricosuria

Predisposition to urate bladder stones

Description: Metabolic disorder resulting in elevated levels of uric acid in blood and urine. This trait predisposes dogs to form urate bladder stones

Symptoms : Difficulty urinating, blood in urine, urinary incontinence, abdominal pain. Some complications are possible: acute kidney failure, urinary tract infection, or rupture of bladder

Age of onset : Between 3 and 6 years old

Frequency :

Gene involved : SLC2A9

Tested mutation : c.616G>T

Transmission : Autosomal Recessive

Patent : _

Notes : Predisposition to urate bladder stones caused by this mutation is variable according to breeds. Most of homozygous mutated dogs never show symptoms.

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F7 - Factor VII Deficiency

Mild bleeding disorder

Giant Schnauzer

F7 - Factor VII Deficiency

Mild bleeding disorder

Description: Deficiency of factor VII, a protein involved in blood coagulation

Symptoms : Excessive gingival haemorrhage during eruption of adult teeth, nose bleeding, skin bruising, prolonged bleeding after surgery or trauma

Age of onset : From birth

Frequency : Not available

Gene involved : F7

Tested mutation : c.287G>A

Transmission : Autosomal Recessive

Patent : -

Notes :

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55€ Order

Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten

45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat

Programme de recherche

Research program

ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests

Melanoma

Pigment cell cancer

Giant Schnauzer

Melanoma

Pigment cell cancer

Speciality Oncology

Description : Highly aggressive cancer occurring on the skin surface, in the eye and mucous membranous sites. In this breed, the most commonly encountered type is cutaneous melanoma on fingers.

Symptoms : -

Age of onset : -

Examination : Histological or cytological analyses

Progress : Undergoing sampling

Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)

Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree

Collaboration : Dr C. André (CNRS of Rennes, France)

Contact : cani-dna@univ-rennes1.fr mageane@antagene.com

Comment : -

Programme de recherche

Research program

ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests

Melanoma

Pigment cell cancer

Giant Schnauzer

Melanoma

Pigment cell cancer

Speciality Oncology

Description : Highly aggressive cancer occurring on the skin surface, in the eye and mucous membranous sites. In this breed, the most commonly encountered type is cutaneous melanoma on fingers.

Symptoms : -

Age of onset : -

Examination : Histological or cytological analyses

Progress : Undergoing sampling

Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)

Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree

Collaboration : Dr C. André (CNRS of Rennes, France)

Contact : cani-dna@univ-rennes1.fr mageane@antagene.com

Comment : -