ANTAGENE provides a certificate displaying the genetic status of a dog or a cat
Progressive loss of vision
Description: Rod and cone dysplasia type 4
Symptoms : Progressive loss of vision (at night and then in daylight) culminating in blindness
Age of onset : Average age of 10 years, cases observed from 5 to 12 years old
Frequency : 7% carriers in French population
Gene involved : C2orf71
Tested mutation : c.3149_3150insC
Transmission : Autosomal Recessive
Patent :
Notes : This variant does not account for all cases in the English Setter breed, indicating the presence of at least one additional mutation for PRA in this breed that remains to be identified.
Nervous system degeneration
Description: Neurodegenerative disease leading to loss of motor function and vision and to behavioural disorder
Symptoms : Progressive loss of motor function and coordination, behavioural disorder, blanks, progressive loss of vision
Age of onset : Between 12 and 18 months old
Frequency : _
Gene involved : CLN8
Tested mutation : c.491T>C
Transmission : Autosomal Recessive
Patent : _
Notes : _
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