Dachshund

Dachshund

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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OI - Osteogenesis Imperfecta

Extremely fragile bones and teeth

Dachshund

OI - Osteogenesis Imperfecta

Extremely fragile bones and teeth

Description: Involved protein participates in the collagen synthesis, which is critical for the proper development of the bones

Symptoms : Spontaneous bone and teeth fractures, joint hyperlaxity, possibly hearing loss, dwarfism and dentinogenesis imperfecta

Age of onset : From birth

Frequency : 12% carriers in European Wire-haired Dachshund

Gene involved : SERPINH1

Tested mutation : c.977C>T

Transmission : Autosomal Recessive

Patent : _

Notes : _

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IC - Improper Coat - Furnishings

Type of coat

Dachshund

IC - Improper Coat - Furnishings

Type of coat

Description: DNA test can identifying dogs carrying the trait smooth coat without furnishings also called improper coat in some breeds

Symptoms : Short hair on the head and face, as well as on lower legs

Age of onset : From birth

Frequency : Not available

Gene involved : RSPO2

Tested mutation : 167pb insertion

Transmission : Autosomal Recessive

Patent : -

Notes :

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MERLE - Merle Coat Colour

M locus

Dachshund

MERLE - Merle Coat Colour

M locus

Description: DNA test can identify dogs carrying the genotype "Merle" (M Locus) and highlight double merles and cryptic merles

Symptoms : Patches of diluted pigment intermingled with normal melanin, blue eyes, often associated with a wide range of auditory and ophthalmologic abnormalities. Double merles are predominantly white

Age of onset : From birth

Frequency : Not available

Gene involved : SILV

Tested mutation : SINE insertion

Transmission : Autosomal Dominant

Patent : -

Notes :

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55€ Order

Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten

45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat

Programme de recherche

Research program

ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests

MVD - Mitral Valve Disease

Heart valve defect

Dachshund

MVD - Mitral Valve Disease

Heart valve defect

Speciality Cardiology

Description : Degradation of the mitral valve causing a leak during cardiac contraction and partial regurgitation of blood. Late-onset progressive disorder

Symptoms : Cardiac arrhythmia, cardiac murmur, exercise intolerance, cardiac insufficiency

Age of onset : The average age of onset is between 6 and 8 years, but in some cases, first symptoms appear at 3-4 years old

Examination : Auscultation

Progress : Undergoing sampling

Prélèvements pour participer à la recherche : Blood sample in EDTA tube (2-4 mL)

Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree

Collaboration : Team of Pr Valérie Chetboul (ENVA-UCA, France)

Contact : mageane@antagene.com

Comment : Other name: degenerative mitral valve disease