Chinese Crested Dog

Chinese Crested Dog

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

Order

CMSD-A - Canine Multiple System Degeneration

Movement disorder

Chinese Crested Dog

CMSD-A - Canine Multiple System Degeneration

Movement disorder

Description: Degeneration of the cerebellum, caudate nucleus and substantia nigra resulting in nervous disorder

Symptoms : Cranial intention tremor, goose-stepping gait (ataxia), falling episodes, severe and progressive movement disorder

Age of onset : Between 3 and 6 months old

Frequency : Not available

Gene involved : SERAC1

Tested mutation : c.182+1_182+4delGTAA

Transmission : Autosomal Recessive

Patent : -

Notes :

PrintSend to a friendPartager sur Facebook

Order

PLL-A - Primary Lens Luxation

Lens displacement in the eye

Chinese Crested Dog

PLL-A - Primary Lens Luxation

Lens displacement in the eye

Description: Partial or complete breakdown of the zonular ligaments suspending the lens

Symptoms : Reddened eye, pain, corneal oedema, glaucoma which can damage the optic nerve causing blindness

Age of onset : Between 3 and 8 years old

Frequency : 43%

Gene involved : ADAMTS17

Tested mutation : c.1473+1G>A

Transmission : Autosomal Recessive

Patent : _

Notes : Primary lens luxation affects both eyes although few weeks or few months can separate luxation from each eye.

PrintSend to a friendPartager sur Facebook

Order

PRA-rcd3 - Progressive Retinal Atrophy

Progressive loss of vision

Chinese Crested Dog

PRA-rcd3 - Progressive Retinal Atrophy

Progressive loss of vision

Description: Rod and cone dysplasia type 3

Symptoms : Progressive loss of vision (at night and then in daylight) culminating in blindness

Age of onset : Between 6 months and 3 years old

Frequency : Not available

Gene involved : PDE6A

Tested mutation : c.1940delA

Transmission : Autosomal Recessive

Patent : -

Notes : Another DNA test (PRA-prcd) is available to detect another form of PRA in this breed.

PrintSend to a friendPartager sur Facebook

Order

PRA-prcd - Progressive Retinal Atrophy

Progressive loss of vision

Chinese Crested Dog

PRA-prcd - Progressive Retinal Atrophy

Progressive loss of vision

Description: Progressive rod-cone degeneration

Symptoms : Declining vision (at night and then in daylight) and eventual blindness

Age of onset : Between 2 and 12 years old

Frequency : Not available

Gene involved : PRCD

Tested mutation : c.5G>A

Transmission : Autosomal Recessive

Patent : -

Notes : Another DNA test (PRA-rcd3) is available to detect another form of PRA in this breed.

PrintSend to a friendPartager sur Facebook

Order

VWD2 - von Willebrand's Disease Type II

Moderate to severe bleeding disorder

Chinese Crested Dog

VWD2 - von Willebrand's Disease Type II

Moderate to severe bleeding disorder

Description: Low level and abnormal function of von Willebrand factor, a protein involved in blood coagulation

Symptoms : Important bleedings or haemorrhagic episodes, potentially lethal, excessive gingival haemorrhage during eruption of adult teeth, nose bleeding, skin bruising, prolonged bleeding after surgery or trauma

Age of onset : From birth

Frequency : Not available

Gene involved : VWF

Tested mutation : A>G in a2 domain

Transmission : Autosomal Recessive

Patent : -

Notes :

PrintSend to a friendPartager sur Facebook

Order

NCL-G - Neuronal Ceroid Lipofuscinosis

Nervous system degeneration

Chinese Crested Dog

NCL-G - Neuronal Ceroid Lipofuscinosis

Nervous system degeneration

Description: Neurodegenerative disease leading to loss of motor function and vision and to behavioural disorder

Symptoms : Progressive loss of motor function and coordination (ataxia), visual impairment, behavioural disorder, cognitive decline

Age of onset : Between 12 and 18 months old

Frequency : Not available

Gene involved : MFSD8

Tested mutation : c.843delT

Transmission : Autosomal Recessive

Patent : -

Notes :

PrintSend to a friendPartager sur Facebook

Order

CED - Ectodermal Dysplasia

Hairlessness

Chinese Crested Dog

CED - Ectodermal Dysplasia

Hairlessness

Description: Abnormal development of any tissue of ectodermal origin

Symptoms : Hairlessness except for the top of the head, the edges of the limbs and the tail, dental abnormalities

Age of onset : From birth

Frequency : Not available

Gene involved : FOXI3

Tested mutation : c.57_63dup7

Transmission : Autosomal Dominant

Patent : -

Notes :

PrintSend to a friendPartager sur Facebook

45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat

55€ Order

Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten