Australian Cattle Dog

Australian Cattle Dog

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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MDR1 - Multidrug Sensitivity

Poisoning after drug admission

Australian Cattle Dog

MDR1 - Multidrug Sensitivity

Poisoning after drug admission

Description: Abnormal function of a blood-brain barrier protein resulting in neurotoxicity due to admission of some drugs

Symptoms : hypersalivation, vomiting, ataxia, blindness, tremor, depression, coma, possibly death

Age of onset : From birth

Frequency : Not available

Gene involved : MDR1

Tested mutation : c.295_298del

Transmission : Autosomal Codominant

Patent : VHL Licence

Notes : For more information about concerned drugs: www.vetmed.wsu.edu/depts-VCPL/drugs.aspx Heterozygotes may be subject to poisoning, with high variability between breeds, individuals, molecules and intake.

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PLL-A - Primary Lens Luxation

Lens displacement in the eye

Australian Cattle Dog

PLL-A - Primary Lens Luxation

Lens displacement in the eye

Description: Partial or complete breakdown of the zonular ligaments suspending the lens

Symptoms : Reddened eye, pain, corneal oedema, glaucoma which can damage the optic nerve causing blindness

Age of onset : Between 3 and 8 years old

Frequency : Not available

Gene involved : ADAMTS17

Tested mutation : c.1473+1G>A

Transmission : Autosomal Recessive

Patent : _

Notes : Primary lens luxation affects both eyes although few weeks or few months can separate luxation from each eye.

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PRA-prcd - Progressive Retinal Atrophy

Progressive loss of vision

Australian Cattle Dog

PRA-prcd - Progressive Retinal Atrophy

Progressive loss of vision

Description: Progressive rod-cone degeneration

Symptoms : Declining vision (at night and then in daylight) and eventual blindness

Age of onset : Between 2 and 12 years old

Frequency : Not available

Gene involved : PRCD

Tested mutation : c.5G>A

Transmission : Autosomal Recessive

Patent : -

Notes : Another DNA test (PRA-rcd4) is available to detect another form of PRA in this breed.

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PRA-rcd4 - Progressive Retinal Atrophy

Progressive loss of vision

Australian Cattle Dog

PRA-rcd4 - Progressive Retinal Atrophy

Progressive loss of vision

Description: Rod and cone dysplasia type 4

Symptoms : Progressive loss of vision (at night and then in daylight) culminating in blindness

Age of onset : Average age of 10 years, cases observed from 5 to 12 years old

Frequency : Not available

Gene involved : C2orf71

Tested mutation : c.3149_3150insC

Transmission : Autosomal Recessive

Patent : -

Notes : Another DNA test (PRA-prcd) is available to detect another form of PRA in this breed.

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45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat

55€ Order

Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten