Altdeutsche Schäferhunde

Altdeutsche Schäferhunde

45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat

55€ Order

Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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DM - Degenerative Myelopathy

Progressive paralysis

Altdeutsche Schäferhunde

DM - Degenerative Myelopathy

Progressive paralysis

Description: Degenerative disease of the spinal cord causing progressive paralysis

Symptoms : Loss of coordination (ataxia) in the hind limbs until paraplegia, loss of urinary and fecal continence. If signs progress for a longer period of time, eventually weakness will develop in the front limbs.

Age of onset : Between 8 and 14 years old

Frequency : _

Gene involved : SOD1

Tested mutation : c.118G>A

Transmission : Autosomal Recessive

Patent : _

Notes :

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NAH - Pituitary Dwarfism

Growth retardation

Altdeutsche Schäferhunde

NAH - Pituitary Dwarfism

Growth retardation

Description: Underdevelopment of the pituitary gland leading to pituitary hormone deficiency causing growth retardation

Symptoms : Marked growth retardation, small size, retention of puppy coat, lack of adult coat, bilateral symetrical loss of hair coat mostly located at the trunk, the neck and at the top of the legs Less frequent signs : hyperpigmentation of the skin, scales, bacterial infections

Age of onset : Significated clinical signs 2-3 months after birth

Frequency : -

Gene involved : LHX3

Tested mutation : 7bp del intron 5 affects splice site

Transmission : Autosomal Recessive

Patent : -

Notes :

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DIL - Dilution

Lighter coat colour

Altdeutsche Schäferhunde

DIL - Dilution

Lighter coat colour

Description: DNA test can identifying dogs carrying the genotype "Dilute" (D Locus)

Symptoms : Dilution or lightening effect of the solid colours

Age of onset : From birth

Frequency :

Gene involved : MLPH

Tested mutation : c.-22G>A

Transmission : Autosomal Recessive

Patent :

Notes :

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PL - Hair Length

Long coat / Short coat

Altdeutsche Schäferhunde

PL - Hair Length

Long coat / Short coat

Description: DNA test can identifying dogs carrying the genotype "Long Coat"

Symptoms : _

Age of onset : _

Frequency : -

Gene involved : FGF5

Tested mutation : c.284G>T

Transmission : Autosomal Recessive

Patent : _

Notes : _

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