British Shorthair

British Shorthair

75€ (Except SH and OPTIGEN tests)

Antagene Séléction

DNA - based testing for hereditary diseases

ANTAGENE provides a certificate displaying the genetic status of a dog or a cat

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CP - Colour Point

Pale body and relatively darker extremities

British Shorthair

CP - Colour Point

Pale body and relatively darker extremities

Description: DNA test can identifying cats carrying the genotype "Colour-Point"

Symptoms : _

Age of onset : _

Frequency : _

Gene involved : TYR

Tested mutation : G302R

Transmission : Autosomal Recessive

Patent : _

Notes : The test can not be used to detect genetically other pattern, like Sepia or Mink, or the coat colours.

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PKD - Polycystic Kidney Disease

Kidney failure

British Shorthair

PKD - Polycystic Kidney Disease

Kidney failure

Description: Cysts compressing the renal tissue and preventing a correct kidney functioning

Symptoms : Excessive water consumption, excessive urine volume, weight loss, vomiting, lethargy, chronic and ultimately fatal renal failure

Age of onset : Between 2 and 10 years old

Frequency : The initial study showed 12% carriers. Currently, the frequency is 1% carriers in the tested population

Gene involved : PKD1

Tested mutation : C.10063C>A

Transmission : Autosomal Dominant

Patent : _

Notes : The study of PKD mutation frequency shows a significant decrease since 2006 in the tested population.

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55€ Order

Antagene Parenté

DNA - Certified parentage

ANTAGENE performs genetic identification and parentage verification for a puppy and a kitten

45€ Order

Antagene Identité

Genetic Identification

ANTAGENE produces an unique genetic fingerprint of a dog or a cat

Programme de recherche

Research program

ANTAGENE is involved into discovering the causes of hereditary diseases and developp new DNA screening tests

HCM - Hypertrophic Cardiomyopathy

Thickening of the heart muscle

British Shorthair

HCM - Hypertrophic Cardiomyopathy

Thickening of the heart muscle

Speciality Cardiology

Description : Progressive thickening of the cardiac muscle, notably a left ventricular hypertrophy, thereby obstructing the outflow of blood. Cardiac function is impaired.

Symptoms : Cardiac arrhythmia, cardiac murmur, breathing difficulty, exercise intolerance, fatigability, vomiting, cough, anorexia. The disease can lead to a fatal outcome for the cat, sometimes sudden death can occur without symptoms.

Age of onset : -

Examination : Echocardiography

Progress : Undergoing sampling

Prélèvements pour participer à la recherche : Blood sample in EDTA tube (1-3 mL) or, failing that, a cheek swab (with 2 cytobrushes). In case of death, whatever the reason : • Sample and put promptly the whole heart in formalin for histological analysis, and a piece of tissue in alcohol (e.g. tong

Documents to be attached to samples : Clinical certificate, Sampling certificate, Copy of pedigree

Collaboration : -

Contact : mageane@antagene.com

Comment : Antagene already offers a DNA test for cardiomyopathy in Maine Coon and Ragdoll.